GenDB is Taueret's expansive, proprietary genealogy database. The extensive database of multi-generational genealogical records provides an unparalleled resource for genetic research of diseases and disorders. Several collaborators have used GenDB to expedite disease gene discoveries.
GenDB documents the relationships between over 30 million ancestors of the present day western U.S. population and was constructed from more than 50,000 genealogy data sources in the public domain. More than 60% of the individuals in the database have 10 or more generations of ancestors. In many instances, pedigrees including more than 25 generations have been constructed through GenDB. With a proprietary algorithm that maximizes relevant relationships, GenDB is the most useful database of its kind.
How can GenDB advance your genetic research?
This unique resource is used to document extended pedigrees for the purpose of establishing heritability and strengthening clinical and phenotypic data on test subjects. GenDB provides substantial evidence to determine the likelihood of common conditions having genetic relationships prior to any live sample processing, potentially averting significant laboratory expenses. Furthermore, use of the proprietary database provides an additional layer to validate gene research results.
Knowing the extent of common ancestry greatly speeds up the disease genetics approach, reducing the complexity of complex diseases. By knowing the historical familial link between apparently unrelated individuals, scientists can perform sophisticated identity-by-descent approaches to finding disease genes. GenDB can provide your team of medical researchers and investigators with unprecedented access to the large, multi-generational Utah families whose genealogical records provide an unparalleled resource for human genetic analysis.
To find out how GenDB can complement your genetic investigations, and to discuss collaborative research opportunities, contact us.